BSE612A - Biochemical Engineering
Prerequisites:
3-0-0-9
Course Contents
- Introduction to biochemical engineering, bioprocesses, bio-products and biochemical technology with specific examples Three lectures.
- Upstream process: Microbial, mammalian and plant systems for bioprocess technology. Sterilization. Stoichiometry and energetic of microbial metabolism. Transport phenomena Five lectures.
- Enzyme catalyzed reactions and processes. Cell and enzyme immobilization. Bioreactor design and applications. Instrumentation and control Six lectures.
- Downstream process: Bio-separations, characteristics of biological materials, pretreatment methods, separation of cell biomass, adsorption, filtration, centrifugation, precipitation and extraction Four lectures.
- Liquid chromatography principles, plate and rate theory, ion exchange, gel filtration, affinity chromatography, hydrophobic interaction and reverse phase chromatography Six lectures
- Integrated bioprocesses Bioprocess integration for efficient production and recovery, expanded bed separations, affinity precipitations, aqueous two phase processes, monolithic chromatographic separations Six lectures.
- Polishing, crystallization, drying, scale up consideration, process monitoring and process economics Three lectures
- Environmental bioprocesses Interaction of mixed microbial population, biological wastewater treatment, anaerobic digesters, bio-remediation Three lectures.
- Case studies and new developments of bioprocesses paper readings and presentations.
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